Context. - Physical activity and fitness are believed to reduce premature mortality, but whether genetic factors modify this effect is not known.
- To investigate leisure physical activity and mortality with respect to familial aggregation of health habits during childhood and factors that may enable some individuals to achieve higher levels of fitness.
- Prospective twin cohort study.
- In 1975, at baseline, 7925 healthy men and 7977 healthy women of the Finnish Twin Cohort aged 25 to 64 years who responded to a questionnaire on physical activity habits and known predictors of mortality.
Those who reported exercising at least 6 times per month with an intensity corresponding to at least vigorous walking for a mean duration of 30 minutes were classified as conditioning exercisers, those who reported no leisure physical activity were classified as sedentary, and other subjects were classified as occasional exercisers.
- All-cause mortality and discordant deaths among same-sex twin pairs from 1977 through 1994.
- Among the entire cohort, 1253 subjects died.
The hazard ratio for death adjusted for age and sex was 0.71 (95% confidence interval [Cl], 0.62-0.81) in occasional exercisers and 0.57 (95% Cl, 0.45-0.74) in conditioning exercisers, compared with those who were sedentary (Pfor trend<. 001). (...)
Mots-clés Pascal : Sport, Loisir, Prévention, Mortalité, Etude cohorte, Prospective, Caractère génétique, Relation familiale, Homme
Mots-clés Pascal anglais : Sport, Leisure, Prevention, Mortality, Cohort study, Prospective, Genetic character, Familial relation, Human
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0139094
Code Inist : 002A24. Création : 21/07/1998.