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  1. Seroprevalence of Helicobacter pylori infection in Nepal : low prevalence in an isolated rural village.

    Article - En anglais

    Objective To determine the seroprevalence of Helicobacter pylori infection in Nepal.

    Design H

    Pylori infection was identified using a specific and sensitive enzyme-linked immunosorbent assay for anti-H. pylori immunoglobulin G. Study population Serum samples were collected from 1142 inhabitants (age range 4-93 years) from two villages : Kotyang, a rural isolated village (250 men, 210 women) and Bhadrakali, a suburban village of Kathmandu (334 men, 348 women).

    Results The overall prevalence of H

    Pylori infection was 56.8%, while a significantly higher prevalence was found in the suburban village (Bhadrakali ; 67.2%) than in the rural village (Kotyang ; 41.5%). This difference was generally reflected by the infection rate in the 10-14-year-old age-group (Bhadrakali, 60% compared with Kotyang, 22.2%). The prevalence of infection significantly increased with age, while no significant difference was found in the prevalence of infection by gender.

    There was no difference in H. pylori positivity between individuals with and without upper abdominal symptoms in both villages.

    Conclusion There was a significant regional difference in the seroprevalence of H. pylori within Nepal, which showed lower prevalence in an isolated rural village.

    This difference was mainly caused by the different acquisition rate in teenagers, thus indicating that the teenage lifestyle of this particular environment seemed to be the major determinant in the acquisition of H. (...)

    Mots-clés Pascal : Gastrite, Campylobactériose, Bactériose, Infection, Helicobacter pylori, Spirillaceae, Spirillales, Bactérie, Incidence, Séropositivité, Prévalence, Milieu rural, Relation, Isolement géographique, Age, Etude statistique, Homme, Appareil digestif pathologie, Estomac pathologie

    Mots-clés Pascal anglais : Gastritis, Campylobacter infection, Bacteriosis, Infection, Helicobacter pylori, Spirillaceae, Spirillales, Bacteria, Incidence, Seropositivity, Prevalence, Rural environment, Relation, Geographical isolation, Age, Statistical study, Human, Digestive diseases, Gastric disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0137430

    Code Inist : 002B30A01A2. Création : 21/07/1998.