Using data from a randomized trial of tirilazad mesylate, we assessed the differences between Canada and the United States in the use of medical resources and outcomes in the treatment of aneurysmal subarachnoid hemorrhage during the first 90 days after admission to the hospital.
Methods-Of the 877 patients for whom economic data were available, 194 were enrolled in Canada and 683 were enrolled in the United States.
The differences between the countries in patient characteristics, use of medical resources, and outcomes were analyzed by comparing means and the 95% confidence intervals (CIs) around the differences in means.
These differences also were predicted with use of multivariable regression analysis.
The average hospital stay was 4.2 days longer (95% CI, 1.3 to 7.1 days) in Canada, but most of the extra stay was among patients admitted to the study in poor neurological condition.
In general, however, hospital stays in Canada were substantially less intensive.
Patients treated in Canada spent 3.7 fewer days (95% CI, 1.2 to 6.1 days) in nursing homes and rehabilitation centers than did patients in the United States.
No statistically significant differences were seen for Glasgow Outcome Scale score, death, and occurrence of vasospasm. (...)
Mots-clés Pascal : Anévrysme, Artère, Intracrânien, Hémorragie, Sousarachnoïdien, Gestion, Traitement, Ressource, Evolution, Pronostic, Etude comparative, Homme, Système nerveux pathologie, Système nerveux central pathologie, Encéphale pathologie, Cérébrovasculaire pathologie, Appareil circulatoire pathologie, Vaisseau sanguin pathologie, Artère pathologie
Mots-clés Pascal anglais : Aneurysm, Artery, Intracranial, Hemorrhage, Subarachnoid, Management, Treatment, Resource, Evolution, Prognosis, Comparative study, Human, Nervous system diseases, Central nervous system disease, Cerebral disorder, Cerebrovascular disease, Cardiovascular disease, Vascular disease, Arterial disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0135680
Code Inist : 002B17C. Création : 21/07/1998.