Differences in medical and surgical therapy for stroke prevention between leading experts in North America and Western Europe.
Background and Purpose-Large multicenter trials have evaluated the benefit of different medical and surgical therapies to prevent stroke.
However, the application of trial results to clinical practice remains uncertain for some areas of stroke prevention and has been discussed passionately among international experts.
As part of a worldwide survey, the purpose of this analysis was to provide an informative and comparative view of the current practice of leading experts in North America (NA) and Western Europe (WE), where most of the large prevention trials have been performed.
Methods-The survey was performed worldwide among 185 neurologists who are currently leading the discussions of stroke prevention practices.
It contained questions on the use of antiplatelet agents, oral anticoagulation, and surgery for the prevention of ischemic stroke.
The population of this present analysis is the two groups of experts from WE (n=73) and NA (n=48) exclusively.
Of each group,>90% responded to the survey.
Nearly all respondents reported prescribing aspirin in patients at risk of atherothrombotic stroke, but significant differences between NA and WE are shown by the recommended doses (P<. 0001) : aspirin doses of>500 mg daily are given exclusively by American participants (36%), whereas doses<200 mg are recommended only in Europe (51%). Eighty-six percent of American versus 59% of European respondents reported using ticlopidine as their second choice. (...)
Mots-clés Pascal : Accident cérébrovasculaire, Prévention, Chimiothérapie, Anticoagulant, Chirurgie, Vaisseau sanguin, Fibrillation auriculaire, Etude comparative, Etats Unis, Amérique du Nord, Amérique, Europe, Homme, Système nerveux pathologie, Système nerveux central pathologie, Encéphale pathologie, Cérébrovasculaire pathologie, Appareil circulatoire pathologie, Vaisseau sanguin pathologie, Cardiopathie, Trouble rythme cardiaque, Trouble excitabilité
Mots-clés Pascal anglais : Stroke, Prevention, Chemotherapy, Anticoagulant, Surgery, Blood vessel, Atrial fibrillation, Comparative study, United States, North America, America, Europe, Human, Nervous system diseases, Central nervous system disease, Cerebral disorder, Cerebrovascular disease, Cardiovascular disease, Vascular disease, Heart disease, Arrhythmia, Excitability disorder
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0135678
Code Inist : 002B17C. Création : 21/07/1998.