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  1. Fulltext. Relations of cigarette smoking and dietary antioxidants with placental calcification.

    Article - En anglais


    Associations between maternal cigarette smoking and accelerated placental maturation measured as tissue calcification have been reported.

    The authors sought to address whether intakes of the dietary antioxidants, vitamin C, alpha-tocopherol, and beta-carotene, were related to placental calcification of the maternal surface and villi in a cohort of smokers and nonsmokers at risk for delivering small-for-gestational age infants.

    Gross and histologic examination of placentas were used to determine calcification at the surface (n=1,213) and villus sites (n=730), respectively, in a prospective study of black and white women who delivered singleton births between December 1985 and October 1988 at the University of Alabama at Birmingham Hospital in Birmingham, Alabama.

    Controlling for race and gestational age, likelihood of surface and villus calcification increased as smoking levels increased.

    Significant reductions in villus calcification were related to alpha-tocopherol intake after controlling for smoking and gestation while intakes of beta-carotene and vitamin C were related to significant reductions in calcification for black but not white women.

    Surface calcification was not found to be related to antioxidant intake.

    The authors'findings confirm a pathologic relation between smoking and placental calcification and suggest that dietary antioxidants may reduce villus calcification.

    Mots-clés Pascal : Tabagisme, Mère, Gestation pathologie, Placenta, Maturation, Calcification, Oxydation, Régime alimentaire, Antioxydant, Epidémiologie, Facteur risque, Foetus, Etude comparative, Angleterre, Grande Bretagne, Royaume Uni, Europe, Placenta pathologie, Alimentation

    Mots-clés Pascal anglais : Tobacco smoking, Mother, Pregnancy disorders, Placenta, Ripening, Calcification, Oxidation, Diet, Antioxidant, Epidemiology, Risk factor, Fetus, Comparative study, England, Great Britain, United Kingdom, Europe, Placenta diseases, Feeding

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0129481

    Code Inist : 002B20F02. Création : 22/06/1998.