To date, a number of reports have been published on the relation of cigarette smoking to age-related maculopathy, an important cause of blindness in the United States.
However, few studies have examined the relation between smoking and the incidence of age-related maculopathy.
In this report, the authors examine this association in persons aged 43-86 years (n=3,583) at baseline who were participants in the baseline examination and 5-year follow-up of the Beaver Dam Eye Study, Beaver Dam, Wisconsin (1988-1990 and 1993-1995).
Exposure data on cigarette smoking were obtained from questions about present and past smoking, duration of smoking, and the number of cigarettes smoked per day.
Age-related maculopathy status was determined by grading stereoscopic color fundus photographs using the Wisconsin Age-related Maculopathy Grading System.
After controlling for age, sex, vitamin supplement use, and beer consumption, men who smoked greater amounts of cigarettes were more likely to develop early age-related maculopathy (odds ratio (OR) per 10 pack-years smoked=1.06,95% confidence interval (Cl) 1.00-1.13, p=0.06) than men who had smoked less.
This association was not observed in women.
Men (OR=3.21,95% Cl 1.09-9.45) and women (OR=2.20,95% Cl 1.04-4. (...)
Mots-clés Pascal : Tabagisme, Maculopathie, Age, Epidémiologie, Facteur risque, Incidence, Homme, Etats Unis, Amérique du Nord, Amérique, Oeil pathologie
Mots-clés Pascal anglais : Tobacco smoking, Maculopathy, Age, Epidemiology, Risk factor, Incidence, Human, United States, North America, America, Eye disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0129478
Code Inist : 002B09N. Création : 22/06/1998.