During the period from January to May 1994, the prevalence of antibodies to hepatitis A virus infection (anti-HAV) was tested by immunoenzyme assay in the serum samples of 620 apparently healthy subjects (81% males, 19% females), from 10 to 29 years old, resident in North-East Italy (Pordenone and surrounding district).
The overall prevalence of anti-HAV was 3.7%. There was a significant lower prevalence in the group aged 10-19 than in the one aged 20-29 years (0.7% vs 6% ; p<0.001).
Moreover, a significant sex difference was observed for the 20-29 year age group (p<0.001).
Among the various risk factors considered, family size and travelling abroad to endemic areas were significantly associated with HAV infection.
Since a valid and effective vaccine against HAV infection has recently become available, anti-HAV vaccination campaigns can feasibly be programmed.
However, different geographical regions present different epidemiological situations, so its use should be adapted to each region, with special attention to the cost-effectiveness of the immunisation programme.
Our data suggest that in our region such vaccination could initially be proposed to high-risk subjects such as those travelling to endemic areas.
Mots-clés Pascal : Hépatite virale A, Virose, Infection, Sérologie, Epidémiologie, Incidence, Prévalence, Facteur risque, Adulte jeune, Homme, Italie, Europe, Appareil digestif pathologie, Foie pathologie
Mots-clés Pascal anglais : Viral hepatitis A, Viral disease, Infection, Serology, Epidemiology, Incidence, Prevalence, Risk factor, Young adult, Human, Italy, Europe, Digestive diseases, Hepatic disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0129215
Code Inist : 002B05C02G. Création : 22/06/1998.