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  1. Economic costs of expanded criteria donors in renal transplantation.

    Article, Communication - En anglais

    Annual Meeting of the American Society of Transplant Surgeons. Chicago, IL, USA, 1997/05/11.


    The organ shortage has increased interest in the use of « expanded criteria » donors (ECDs).

    Although much has been written concerning the clinical outcomes associated with the use of such donors, little has been published concerning the financial results associated with their use.


    A retrospective cost identification study of recipients of kidneys from expanded criteria cadaveric donors was used.


    Of a total of 78 cadaveric renal transplants in fiscal year 1995, there were 38 kidneys (49%) transplanted from ECDs.

    Graft survival at 1 year was not statistically different between patients who received kidneys from ECDs and those who received non-ECD kidneys (84% vs. 85%, respectively).

    Length of stay (P<0.05), serum creatinine at 1 year after transplantation (P<0.01), and the percentage of patients requiring hemodialysis (P<0.05) were all higher among patients who received kidneys from ECDs.

    Cold ischemic time was significantly longer in patients who received kidneys from ECDs (31.4±12 hr vs. 24.0±9 hr ; P<0.05).

    The total average and median costs were $12,190 and $10,911 higher in recipients of kidneys from ECDs as compared with non-ECD controls (P<0.01).

    Stepwise linear regression demonstrated that length of stay was the major clinical determinant of total costs ; only the use of antilymphocyte induction was otherwise significantly associated. (...)

    Mots-clés Pascal : Don organe, Homme, Economie santé, Rein, Critère sélection, Donneur

    Mots-clés Pascal anglais : Organ donation, Human, Health economy, Kidney, Selection criterion, Donor

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0127890

    Code Inist : 002B27C. Création : 22/06/1998.