Zinc deficiency has been seen in developing countries in which grain-based vegetable protein is consumed more often than animal protein.
This study was done to emphasize the importance of zinc-fortified foods and to investigate bioavailability of zinc in zinc-fortified bread.
Serum zinc concentrations in healthy 7-to 11-year-old school children were determined.
In 24 of 101 children serum zinc concentrations were below 65 mug/dl.
These 24 children with asymptomatic zinc deficiency were divided into two equal groups.
The 12 children with low serum zinc concentrations received the zinc-fortified bread providing 2 mg/kg/day elemental zinc acetate for 90 days (zinc-supplemented group), whereas the other 12 children received the same quality bread with no zinc fortification (control group).
By the end of the period, the zinc-supplemented group had significantly higher serum and leukocyte zinc concentrations (p<0.01) and the weight, serum albumin levels, and alkaline phosphatase increased (p<0.01).
Immune functions improved, evidenced by conversion of delayed hypersensitivity skin reactions.
Zinc-fortified bread (2 mg/kg/day) caused no side effects or manifestations of zinc toxicity.
The results indicate that the bioavailability of zinc in the bread is satisfactory.
The use of zinc-fortified bread was found to be an economical and readily accessible method to eliminate zinc deficiency and to prevent further occurrence.
Mots-clés Pascal : Déficit, Oligoélément, Zinc, Asymptomatique, Effet biologique, Régime alimentaire enrichi, Pain, Age scolaire, Intérêt, Etude statistique, Enfant, Homme, Métabolisme pathologie, Trouble nutrition, Nutrition
Mots-clés Pascal anglais : Deficiency, Trace element (nutrient), Zinc, Asymptomatic, Biological effect, Supplemented diet, Bread, School age, Interest, Statistical study, Child, Human, Metabolic diseases, Nutrition disorder, Nutrition
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0123635
Code Inist : 002B02N. Création : 22/06/1998.