logo BDSP

Base documentaire


Votre avis nous intéresse

Le réseau BDSP met en oeuvre un projet d'innovation et d'amélioration de ses services, dans le souci constant de proposer des contenus de qualité adaptés aux besoins des utilisateurs.

Identifier de nouvelles sources de financements est la condition nécessaire pour assurer la poursuite et la pérennité de cet outil unique qu'est la BDSP, tout en le faisant évoluer.

Pour définir un nouveau modèle économique, nous avons besoin de votre avis : merci de répondre à notre enquête (temps estimé : 5 minutes).

Participer maintenant
Participer plus tard J'ai déjà participé

  1. Use of a microquantity enzyme immunoassay in a large-scale study of measles, mumps, and rubella immunity in Italy.

    Article - En anglais

    The seroprevalence of antibodies to measles, mumps, and rubella viruses (MMR) was determined in 1498 subjects in Catania, Italy, ranging in age from 1 month to 25 years.

    The study population was divided into seven age groups and screened by enzyme immunoassay using microquantities (10 mul) of whole blood collected by fingerprick on filterpaper discs.

    The results showed that seroconversion for measles (87.6%) and mumps (73.2%) occurred between 6 and 10 years of age.

    The seroprevalence of antibodies to rubella virus increased slowly through the age groups, reaching the highest rate (93.3%) between 16 and 20 years of age.

    Passively transmitted maternal antibodies to mumps and rubella were absent in babies between 5 and 8 months of age, and a few cases positive for measles antibodies were found among babies 6 and 7 months of age.

    The enzyme immunoassay was demonstrated to be suitable for low-cost large-scale screening for MMR immunity.

    The rate of vaccine failure was also evaluated and found to be 9.5% for the measles virus, 12.9% for the mumps virus and 0.0% for the rubella virus.

    Mots-clés Pascal : Rougeole, Virose, Infection, Oreillons, Rubéole, Sérologie, Prévalence, Epidémiologie, Méthode immunoenzymatique, Echec, Vaccination, Italie, Europe, Homme, Exploration immunologique, Séroconversion

    Mots-clés Pascal anglais : Measles, Viral disease, Infection, Mumps, Rubella, Serology, Prevalence, Epidemiology, Enzyme immunoassay, Failure, Vaccination, Italy, Europe, Human, Immunological investigation

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0123478

    Code Inist : 002B05C02C. Création : 22/06/1998.