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  1. The histidin-rich glycoprotein Pro186/Ser polymorphism is not related to myocardial infarction in the ECTIM study.

    Article - En anglais

    The histidin-rich glycoprotein (HRG) may contribute to coronary heart disease as a consequence of its possible thrombophilic properties.

    To test this hypothesis we have investigated the Pro186/Ser polymorphism of the HRG gene, which is known to strongly affect plasma HRG levels, in a large multicenter case-control study of myocardial infarction (MI).

    The results failed to demonstrate any association between the polymorphism and MI or angiographically assessed coronary stenosis.

    Mots-clés Pascal : Infarctus, Myocarde, Polymorphisme, Variabilité génétique, Facteur risque, Epidémiologie, Etude cas témoin, France, Europe, Homme, Appareil circulatoire pathologie, Cardiopathie coronaire, Myocarde pathologie, Génétique, Glycoprotéine riche histidine

    Mots-clés Pascal anglais : Infarct, Myocardium, Polymorphism, Genetic variability, Risk factor, Epidemiology, Case control study, France, Europe, Human, Cardiovascular disease, Coronary heart disease, Myocardial disease, Genetics, Histidin rich glycoprotein

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0120831

    Code Inist : 002B12A03. Création : 22/06/1998.