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  1. Is the association between irritable bowel syndrome and abuse explained by neuroticism ? A population based study.

    Article - En anglais

    Background-In outpatients and the community, an association between abuse (particularly sexual abuse) and irritable bowel syndrome (IBS) has been observed, but whether there is a causal link continues to be disputed.

    Aims-To test the hypothesis that psychological factors explain the apparent association between abuse and IBS.

    Methods-A sample of residents of Pen-rith (a Sydney suburb sociodemographically similar to the Australian population) selected randomly from the electoral rolls (that by law include the entire population of age 18 years and above) was mailed a validated self report questionnaire.

    Measured were gastrointestinal (GI) symptoms including the Rome criteria for IBS, abuse (including the standardised Drossman questions), neuroticism (Eysenck Personality Questionnaire), and psychological morbidity (General Health Questionnaire).


    The response rate was 64% (n=730) ; 12% fulfilled the Rome criteria for IBS.

    Overall abuse in childhood (odds ratio (OR)=2.02,95% confidence interval (CI) 1.29 to 3.15) but not adulthood (OR=1.39,95% CI 0.88 to 2.19) was associazted with IBS univariately.

    Neuroticism and psychological morbidity were also univariately associated with abuse in childhood, abuse in adulthood, and IBS, respectively.

    However, by logistic regression, abuse in childhood was not associated with IBS after controlling for age, gender, and psychological factors (OR=1.34,95% CI 0.83 to 2.17). (...)

    Mots-clés Pascal : Côlon irritable, Epidémiologie, Corrélation, Abus sexuel, Facteur risque, Névrotisme, Enquête publique, Effet psychologique, Morbidité, Homme, Appareil digestif pathologie, Intestin pathologie, Psychopathologie, Sexualité

    Mots-clés Pascal anglais : Irritable bowel syndrome, Epidemiology, Correlation, Sexual abuse, Risk factor, Neuroticism, Public inquiry, Psychological effect, Morbidity, Human, Digestive diseases, Intestinal disease, Psychopathology, Sexuality

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0115511

    Code Inist : 002B13B03. Création : 22/06/1998.