BackgrountL Several islands in Micronesia experienced large measles outbreaks, during 1991 through 1994.
Except for Guam, none of the islands had reported measles outbreaks during the previous 20 years.
To characterize the outbreaks, measles surveillance data, hospital records and death certificates were reviewed.
Preoutbreak vaccination coverage rates were assessed by reviewing public health vaccination records.
Viral isolates were genetically sequenced to determine the source of transmission.
Linear regression analysis was performed to assess the effectiveness of outbreak control measures.
Between 1991 and 1994 more than 1300 measles cases and 16 measles-related deaths were reported in Micronesia.
Preoutbreak vaccination coverage rates among 2-year-old children were 55 to 94%. Genetic sequencing of the viral isolates and epidemiologic investigations suggested transmission between islands and new importations from outside of Micronesia.
The highest attack rates were among children ages<5 years (20/1000) and 10 to 19 years (38/1000).
Compared with attack rates among children ages<1 and 10 to 19 years, attack rates were lower among those ages 5 to 9 years, in whom 2-dose vaccination coverage rates were highest (P<0.001).
Early and rapid implementation of mass vaccination campaigns was significantly associated with shorter duration of outbreaks (P=0.049).
Mots-clés Pascal : Rougeole, Virose, Infection, Epidémie, Vaccination, Taux, Programme sanitaire, Lutte sanitaire, Micronésie, Océanie, Facteur risque, Epidémiologie, Homme
Mots-clés Pascal anglais : Measles, Viral disease, Infection, Epidemic, Vaccination, Rate, Sanitary program, Sanitary control, Micronesia, Oceania, Risk factor, Epidemiology, Human
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0107841
Code Inist : 002B05C02C. Création : 22/06/1998.