To describe the epidemiology of HIV-1 infection in pregnant women in the United Kingdom.
Serial unlinked serosurveillance for HIV-1 in neonatal specimens and surveillance through registers of diagnosed maternal and paediatric infections from reporting by obstetricians, paediatricians, and microbiologists.
United Kingdom, 1988-96.
Pregnant women proceeding to live births and their children Main outcome measures : Time trends in prevalence of HIV-1 seropositivity in newborn infants (as a proxy for infection in mothers) ; the proportions of mothers with diagnosed HIV-1 infections, and their characteristics.
HIV-1 prevalence among mothers in London rose sixfold between 1988 and 1996 (0.19% of women tested ; 1 in 520 in 1996).
Apart from in Edinburgh and Dundee, levels remained low in Scotland (0.025% ; 1 in 3970) and elsewhere in the United Kingdom (0.016% ; 1 in 1930).
Over a third of births to infected mothers in 1996 occurred outside London.
In London the reported infections were predominantly among black African women, whereas in Scotland most were associated with drug injecting.
The contribution of reported infection among African women increased over time as that of drug injecting declined.
In Scotland 51% of mothers'infections were diagnosed before the birth. (...)
Mots-clés Pascal : Gestation, Dépistage, SIDA, Virose, Infection, Virus immunodéficience humaine, Lentivirus, Retroviridae, Virus, Incidence, Contamination, Transmission mère enfant, Distribution, Evolution, Epidémiologie, Homme, Femelle, Immunopathologie, Immunodéficit
Mots-clés Pascal anglais : Pregnancy, Medical screening, AIDS, Viral disease, Infection, Human immunodeficiency virus, Lentivirus, Retroviridae, Virus, Incidence, Contamination, Mother to child transmission, Distribution, Evolution, Epidemiology, Human, Female, Immunopathology, Immune deficiency
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0104992
Code Inist : 002B30A01A2. Création : 22/06/1998.