Age-dependent differences in the prevalence of allergic rhinitis and atopic sensitization between an eastern and a western German city.
Recent studies have found a higher prevalence of allergic rhinitis and atopic sensitization among adults living in eastern than those living in western Germany.
We hypothesize that prevalence rates were similar before Germany was divided and diverged after the division.
Because there are no historical data comparing atopic status between the two parts of Germany, we tested this hypothesis by comparing the prevalence of atopy among persons who were born during different decades.
As part of the EC Respiratory Health Survey, a respiratory health questionnaire was mailed to a population-based sample of 8363 subjects aged 20-44 years from a city in the former West Germany (Hamburg) and a city in the former East Germany (Erfurt).
Of the target population, 6428 (77%) subjects responded.
Subsamples of 731 subjects from Erfurt and 1159 subjects from Hamburg participated in medical examinations, including skin prick tests and specific IgE measurements.
Prevalence rates of allergic sensitization were similar in Hamburg and Erfurt for those born in the periods 1946-51 and 1952-61. respectively, but differed between Hamburg and Erfurt subjects born in the period 1962-71.
After adjustment for several potential predictors. the younger subjects from Hamburg had a higher odds ratio (OR) of sensitization than those Hamburg subjects born before 1952 (skin prick test reactivity : OR 2.06, any specific IgE>0.35 kU/l : OR 1.61). (...)
Mots-clés Pascal : Rhinite, Allergie, Prévalence, Epidémiologie, Sensibilisation, Age, Allemagne, Europe, Ouest, Est, Milieu urbain, Etude comparative, Adulte, Homme, ORL pathologie, Nez pathologie, Immunopathologie
Mots-clés Pascal anglais : Rhinitis, Allergy, Prevalence, Epidemiology, Sensitization, Age, Germany, Europe, West, East, Urban environment, Comparative study, Adult, Human, ENT disease, Nose disease, Immunopathology
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0104902
Code Inist : 002B06C02. Création : 22/06/1998.