To assess the Impact of anti-vaccine movements that targeted pertussis whole-cell vaccines, we compared pertussis incidence in countries where high coverage with diphtheria-tetanus-pertussis vaccines (DTP) was maintained (Hungary, the former East Germany, Poland, and the USA) with countries where immunisation was disrupted by anti-vaccine movements (Sweden, Japan, UK, The Russlan Federation, Ireland, Italy, the former West Germany, and Australia).
Pertussis Incidence was 10 to 100 times lower In countries where high vaccine coverage was maintained than In countries where immunisation programs were compromised by anti-vaccine movements.
Comparisons of neighbouring countries with high and low vaccine coverage further underscore the efficacy of these vaccines.
Given the safety and cost-effectiveness of whole-cell pertussis vaccines, our study shows that, far from being obsolete, these vaccines continue to have an important role In global immunisation.
Mots-clés Pascal : Poliomyélite antérieure, Virose, Infection, Dépistage, Contrôle actif, Vaccination, Impact social, Facteur efficacité, Effet groupe voisin, Monde Est, Article synthèse, Homme, Système nerveux pathologie, Système nerveux central pathologie, Moelle épinière pathologie, Immunoprophylaxie, Education santé
Mots-clés Pascal anglais : Acute anterior poliomyelitis, Viral disease, Infection, Medical screening, Active control, Vaccination, Social impact, Effectiveness factor, Neighbouring group effect, Eastern countries, Review, Human, Nervous system diseases, Central nervous system disease, Spinal cord disease, Immunoprophylaxis, Health education
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0103129
Code Inist : 002B05A02. Création : 22/06/1998.