The possible association between the risk of gastric cancer and nitrate and hardness in drinking water from municipal supplies was investigated in a matched case-control study in Taiwan.
Data on gastric cancer deaths among eligible residents in Taiwan from 1987 through 1991 (6,766 cases) were obtained from the Bureau of Vital Statistics of the Taiwan Provincial Department of Health.
Controls were deaths from other causes (6,766 controls) and were matched individually to the cases by sex, year of birth, and year of death.
Data on nitrate-nitrogen (NO3-N) and hardness levels in drinking water throughout Taiwan were collected from the Taiwan Water Supply Corporation (TWSC).
The municipality of residence for cases and controls was assumed to be the source of the subject's nitrate and hardness exposure via drinking water.
There was no difference in gastric cancer rates between the groups with different levels of nitrate.
The odds ratios (95% confidence interval) for death from gastric cancer was 0.95 (0.87-1.03) for the group with water nitrate levels between 0.23 and 0.44 mg/L, and 1.02 (0.93-1.11) for the group with nitrate levels greater than 0.45 mg/L. However, the results show a significant negative relationship between drinking water hardness and gastric cancer mortality.
Odds ratios were 1.16 (1.07-1.26) and 1.65 (1.52-1.79), respectively, for exposure to moderately hard water and soft water compared with the use of hard water. (...)
Mots-clés Pascal : Eau potable, Qualité eau, Taiwan, Asie, Tumeur maligne, Estomac, Homme, Epidémiologie, Mortalité, Nitrate, Toxicité, Dureté eau, Eau distribution, Facteur risque, Appareil digestif pathologie, Estomac pathologie, Etiologie
Mots-clés Pascal anglais : Drinking water, Water quality, Taiwan, Asia, Malignant tumor, Stomach, Human, Epidemiology, Mortality, Nitrates, Toxicity, Water hardness, Tap water, Risk factor, Digestive diseases, Gastric disease, Etiology
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0090143
Code Inist : 002B13B01. Création : 14/05/1998.