Cardiac deaths in epilepsy.
Epilepsy and Sudden Death. International Workshop. London, GBR, 1996/10/28.
A study of heart disease mortality and morbidity in patients with epilepsy in Rochester, Minnesota, U.S.A., is presented.
In a cohort of 725 incident cases of epilepsy followed for approximately 10,000 person-years, 237 deaths and 48 incident cases of ischemic heart disease were noted.
Overall, the cohort mortality rate was 2.1 times that of the general population.
For those with idiopathic epilepsy, the mortality rate was 1.6 times that of the general population.
For ischemic heart disease, the epilepsy cohort experienced a standardized mortality rate (SMR) of 1.6, slightly higher for remote symptomatic than idiopathic epilepsy.
For sudden death as the initial manifestation of heart disease, the SMR was 2.3. The ratio was not significantly higher for those with idiopathic epilepsy but was 3.9 for remote symptomatic epilepsy.
The findings show much lower incidence rates and relative incidence of sudden death than all of the more recent sudden unexpected death in epilepsy studies.
Reasons for this discrepancy are discussed.
Mots-clés Pascal : Epilepsie, Type, Mortalité, Morbidité, Etats Unis, Amérique du Nord, Amérique, Mort subite, Ischémie, Myocarde, Epidémiologie, Incidence, Etude comparative, Homme, Système nerveux pathologie, Système nerveux central pathologie, Encéphale pathologie, Appareil circulatoire pathologie, Vaisseau sanguin pathologie, Cardiopathie coronaire, Myocarde pathologie
Mots-clés Pascal anglais : Epilepsy, Type, Mortality, Morbidity, United States, North America, America, Sudden death, Ischemia, Myocardium, Epidemiology, Incidence, Comparative study, Human, Nervous system diseases, Central nervous system disease, Cerebral disorder, Cardiovascular disease, Vascular disease, Coronary heart disease, Myocardial disease
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Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0084535
Code Inist : 002B17A03. Création : 14/05/1998.