Background Ageing populations are increasing in many countries and bleeding peptic ulcers in patients older than 60 years carry a greater risk of rebleeding and death.
This study aimed to identify the risk factors for rebleeding and death in very elderly patients with peptic ulcer bleeding.
The efficacy of treatment in preventing recurrent bleeding and death in this group of patients was also studied by means of prospective data collection and analysis.
Methods Data relating to 1744 patients treated between September 1985 and January 1994 for peptic ulcer bleeding were collected prospectively and analysed.
Patients were stratified by age to one of three groups : group I (less than 60 years, n=833), group 2 (60-79 years, n=706) and group 3 (80 or more years, n=205).
Results Univariate and multivariate analyses of 21 factors possibly affecting either rebleeding or death identified age greater than 80 years as one of the factors significantly affecting rebleeding and death.
In a comparison of groups 1,2 and 3, the likelihood of rebleeding and death was significantly greater in group 3. Univariate and multivariate analyses for rebleeding and death were performed for each group.
The severity of initial bleeding had a marked bearing on subsequent rebleeding rates for all three groups.
In group 3, however, large ulcer size and impaired liver function were additional factors which correlated significantly with final outcome. (...)
Mots-clés Pascal : Ulcère, Gastroduodénal, Complication, Hémorragie, Récidivant, Vieillard, Homme, Epidémiologie, Facteur risque, Incidence, Mortalité, Etude longitudinale, Appareil digestif pathologie, Estomac pathologie, Intestin pathologie, Appareil circulatoire pathologie, Vaisseau sanguin pathologie
Mots-clés Pascal anglais : Ulcer, Gastroduodenal, Complication, Hemorrhage, Recurrent, Elderly, Human, Epidemiology, Risk factor, Incidence, Mortality, Follow up study, Digestive diseases, Gastric disease, Intestinal disease, Cardiovascular disease, Vascular disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0079028
Code Inist : 002B13B03. Création : 14/05/1998.