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  1. Compliance with doxycycline therapy in sexually transmitted diseases clinics.

    Article - En anglais


    To determine rates of compliance with doxycycline therapy for patients attending two inner city sexually transmitted diseases (STD) clinics using the MEMS (Medication Event Monitoring System) technology (Aprex Corporation, Fremont, CA).


    An observational study.


    Two STD clinics in Brooklyn, New York and Birmingham, Alabama.


    Patients warranting doxycycline as antichlamydial therapy by usual clinical criteria (e.g., documented chlamydial infections, gonococcal urethritis, mucopurulent cervicitis) were enrolled consecutively from both clinics into four separate categories according to gender and the presence or absence of symptoms : symptomatic men (77), asymptomatic men (30), symptomatic women (83), asymptomatic women (33).


    In the clinic area, patients were given their doxycycline in standard 30-dram medication bottles fitted with the MEMS cap, which is capable of recording the date and time of each bottle opening and closing.

    This information was then retrieved using a software program developed by the manufacturer.

    Patients were instructed to return the bottle and cap at the completion of therapy.

    Efforts were made to contact those who did not return their bottles by both telephone and mail.

    Outcome Measures 

    Bottle openings as recorded by the MEMS were considered to represent use of medication. (...)

    Mots-clés Pascal : Maladie sexuellement transmissible, Epidémiologie, Etude comparative, Doxycycline, Critère décision, Facteur efficacité, Dose absorbée, Etiopathogénie, Evaluation, Homme, Tétracycline dérivé, Appareil génital pathologie, Education santé, Antibiotique, Antibactérien

    Mots-clés Pascal anglais : Sexually transmitted disease, Epidemiology, Comparative study, Doxycycline, Decision criterion, Effectiveness factor, Absorbed dose, Etiopathogenesis, Evaluation, Human, Tetracycline derivatives, Genital diseases, Health education, Antibiotic, Antibacterial agent

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0074153

    Code Inist : 002B02P. Création : 14/05/1998.