The Clean Air Act Amendments of 1990 identify hazardous air pollutants and require significant reductions in their release from major emissions sources.
Relevant to control of these substances, governmental agencies and organizations rely on several different cancer and non-cancer endpoint benchmarks, standards gauging the adequacy of measures taken to protect the public.
A comparison of EPA's Reference Dose and Reference Concentration data with the U.S. Agency for Toxic Substances and Disease Registry's chronic Minimal Risk Level data shows agreement with health risk endpoint estimates for most chemicals, although benchmark variations of an order of magnitude or more are found for several others.
Discrepancies arise because of different uncertainty factors and differences in the selection and interpretation of studies used to assess health risks.
Government agencies should seek to further harmonize risk assessment guidelines, data, and their interpretations.
Mots-clés Pascal : Pollution air, Polluant, Produit chimique, Produit dangereux, Toxicité, Analyse risque, Législation, Règlementation substance toxique, Benchmark
Mots-clés Pascal anglais : Air pollution, Pollutant, Chemical product, Dangerous product, Toxicity, Risk analysis, Legislation, Toxic substances control acts, Benchmarks
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0069249
Code Inist : 002B03M03. Création : 14/05/1998.