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  1. Behavioural dynamics of a clinical trial of sunscreens for reducing solar keratoses in Victoria, Australia.

    Article - En anglais

    Objective

    To determine whether the behaviour of participants based on perception of treatment group in a randomised trial contributed to clinical outcome.

    Design-A double blind randomised controlled trial of the effect of daily application of SPF 17 broad spectrum sunscreen cream (or placebo) on solar keratoses.

    Setting-A rural city in Victoria, Australia

    Residents aged 40 years or over were invited by letter to attend for a skin cancer screening check.

    Of these, 588 people with between one and 30 solar keratoses enrolled in the trial and 431 completed the trial, which extended over a six month period that included summer.

    Participants'perceptions of their treatment allocation, adherence with the treatment regimen, adoption of other sun protection behaviours, side effects, and perceptions of change in condition were measured at two monthly intervals.

    Results

    There were no significant differences between those who completed the study and those that did not for sex, age, treatment group, skin type, number of solar keratoses or correct perception of treatment group.

    Thirty per cent of those completing the study correctly guessed their treatment allocation, and people were just as likely to be right as to be wrong when they stated their opinion about their treatment allocation (z=1.04 ; p=0.15). (...)

    Mots-clés Pascal : Produit antisolaire, Essai clinique, Crème, Kératose solaire, Homme, Traitement, Chimiothérapie, Essai thérapeutique contrôlé, Australie, Océanie, Milieu rural, Comportement social, Perception sociale, Dynamique groupe, Observance médicamenteuse, Peau pathologie, Dyskératose, Hyperkératose, Photodermatose, Photosensibilité, Epidémiologie

    Mots-clés Pascal anglais : Sunscreen product, Clinical trial, Cream, Solar keratosis, Human, Treatment, Chemotherapy, Controlled therapeutic trial, Australia, Oceania, Rural environment, Social behavior, Social perception, Group dynamics, Drug compliance, Skin disease, Dyskeratosis, Hyperkeratosis, Photodermatosis, Photosensitivity, Epidemiology

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0057136

    Code Inist : 002B02K. Création : 14/05/1998.