This study evaluated the association of age-related lens opacities with the use of nutritional supplements and demographic factors among 4314 black participants (=40 years) in the population-based Barbados Eye Study.
Lenses were classified at the slit lamp by the Lens Opacities Classification System II (LOCS II) ; a score =2 was used to define the presence of gradable lens opacities, by type.
Lens changes also included prior cataract surgery or cataract too advanced to grade.
Associations with risk factors were evaluated by logistic regression analyses.
The study identified 1800 individuals with lens changes in at least one eye ; 229 had nuclear opacities only ; 851 had cortical opacities only.
Older age and indicators of lower socioeconomic status (low education and/or non-professional occupation), were positively associated with both nuclear (odds ratio [OR]=1.90) and cortical (OR=1.47) opacities.
Women had an increased risk of cortical opacities (OR=1.41).
Regular users of nutritional supplements were less likely to have lens changes (OR=0.78) and, specifically, cortical opacities (OR=0.77).
The association with nutritional supplements was present in those<70 years, but not at older ages.
The study supports the association of lower socioeconomic status with lens changes, including nuclear and cortical lens opacities. (...)
Mots-clés Pascal : Cataracte, Epidémiologie, Facteur risque, Homme, Négroïde, Age, Sexe, Statut socioéconomique, Régime alimentaire enrichi, Vitamine, Elément minéral, Barbade, Antilles, Amérique Centrale, Amérique, Oeil pathologie, Cristallin pathologie, Segment antérieur pathologie
Mots-clés Pascal anglais : Cataract, Epidemiology, Risk factor, Human, Negroid, Age, Sex, Socioeconomic status, Supplemented diet, Vitamin, Inorganic element, Barbados, West Indies, Central America, America, Eye disease, Lens disease, Anterior segment disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0056875
Code Inist : 002B09G. Création : 14/05/1998.