The relation between inflammatory bowel disease (IBD) and osteoporosis has received increasing attention during the past decade.
The prevalence of low bone mass in patients with IBD has been reported to be more than 50%. The development of a quick non-invasive method to diagnose osteoporosis (dual-energy X-ray absorptiometry) provides a practical tool to identify the patient who needs special attention.
The aetiology of the bone disease in patients with IBD has still not been elucidated. but corticosteroids may play a major role.
Studies on the prevention/treatment of IBD-related osteoporosis are scarce.
In a single uncontrolled study hormone replacement therapy proved effective in preventing bone loss in peri-and post-menopausal women with IBD.
A placebo-controlled study showed that supplementation with calcium and vitamin D prevents bone loss in patients with Crohn's disease.
The present paper reviews our current knowledge on the mechanisms and epidemiology of IBD-related bone disease.
Mots-clés Pascal : Ostéoporose, Association, Maladie inflammatoire, Intestin, Prévalence, Etiologie, Classification morphologique, Etude transversale, Traitement, Recommandation, Article synthèse, Homme, Système ostéoarticulaire pathologie, Ostéopathie, Appareil digestif pathologie, Intestin pathologie, Education santé
Mots-clés Pascal anglais : Osteoporosis, Association, Inflammatory disease, Gut, Prevalence, Etiology, Morphological classification, Cross sectional study, Treatment, Recommendation, Review, Human, Diseases of the osteoarticular system, Bone disease, Digestive diseases, Intestinal disease, Health education
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0054014
Code Inist : 002B15A. Création : 14/05/1998.