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  1. Serum total cholesterol and risk of hospitalization, and death from respiratory disease.

    Article - En anglais

    Background

    In earlier studies, serum total cholesterol was inversely associated with death due to respiratory diseases.

    Methods

    Relationships of cholesterol with risk of respiratory diseases were examined between 1978 and 1993 in a health maintenance organization in Northern California (48 188 men, 55 276 women, about 60% white, age range 25-89).

    Incident and fatal endpoints were ascertained using hospital discharge diagnostic codes and underlying cause of death, respectively.

    Results

    An inverse association of cholesterol level with pneumonia/influenza hospitalization was found among men and women except that, contrary to hypothesis, a positive association was seen in women under 55 years of age.

    Inconsistent inverse associations were found in men, but not women, between cholesterol level and hospitalization for chronic obstructive pulmonary disease (COPD).

    Hospitalization for asthma was unrelated to cholesterol level.

    An inverse association existed between cholesterol level and hospitalization for miscellaneous respiratory diseases among men, but not women.

    Exclusion of early hospitalizations tended to attenuate risk for cholesterol level below 4.14 mmol/l, but not the risk gradient across higher cholesterol levels.

    For deaths, cholesterol level was statistically significantly inversely associated only with COPD. (...)

    Mots-clés Pascal : Appareil respiratoire pathologie, Epidémiologie, Homme, Cholestérol, Mortalité, Hospitalisation, Age, Sexe, Lipide, Californie, Etats Unis, Amérique du Nord, Amérique

    Mots-clés Pascal anglais : Respiratory disease, Epidemiology, Human, Cholesterol, Mortality, Hospitalization, Age, Sex, Lipids, California, United States, North America, America

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0051337

    Code Inist : 002B11D. Création : 14/05/1998.