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  1. Measurement of DNA damage after exposure to electromagnetic radiation in the cellular phone communication frequency band (835.62 and 847.74 MHz).

    Article - En anglais

    Mouse C3H 10T1/2 fibroblasts and human glioblastoma U87MG cells were exposed to cellular phone communication frequency radiations to investigate whether such exposure produces DNA damage in in vitro cultures.

    Two types of frequency modulations were studied : frequency-modulated continuous-wave (FMCW), with a carrier frequency of 835.62 MHz, and code-division multiple-access (CDMA) centered on 847.74 MHz.

    Exponentially growing (U87MG and C3H 10T1/2 cells) and plateau-phase (C3H 10T1/2 cells) cultures were exposed to either FMCW or CDMA radiation for varying periods up to 24 h in specially designed radial transmission lines (RTLs) that provided relatively uniform exposure with a specific absorption rate (SAR) of 0.6 Wlkg.

    Temperatures in the RTLs were monitored continuously and maintained at 37 ± 0.3°C. Sham exposure of cultures in an RTL (negative control) and 137Cs gamma-irradiated samples (positive control) were included with every experiment.

    The alkaline comet assay as described by Olive et al. (Exp.

    Cell Res. 198,259-269,1992) was used to measure DNA damage.

    No significant differences were observed between the test group exposed to FMCW or CDMA radiation and the sham-treated negative controls.

    Our results indicate that exposure of cultured mammalian cells to cellular phone communication frequencies under these conditions at an SAR of 0.6 Wlkg does not cause DNA damage as measured by the alkaline comet assay.

    Mots-clés Pascal : Radiolésion, Téléphone, Analyse risque, Bande fréquence, Réseau communication, DNA, Onde électromagnétique, Modulation fréquence, Animal, Homme, Souris, Rodentia, Mammalia, Vertebrata, Fibroblaste, Cellule tumorale, Culture cellulaire, Mesure température, Appareil portatif, Téléphone cellulaire

    Mots-clés Pascal anglais : Radiation injury, Telephone, Risk analysis, Frequency band, Communication network, DNA, Electromagnetic wave, Frequency modulation, Animal, Human, Mouse, Rodentia, Mammalia, Vertebrata, Fibroblast, Tumor cell, Cell culture, Temperature measurement, Portable equipment

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0048246

    Code Inist : 002A08F01. Création : 14/05/1998.