Background Alcohol consumption has both adverse and beneficial effects on survival.
We examined the balance of these in a large prospective study of mortality among U.S. adults.
Methods Of 490,000 men and women (mean age, 56 years ; range, 30 to 104) who reported their alcohol and tobacco use in 1982,46,000 died during nine years of follow-up.
We compared cause-specific death rates and rates of death from all causes across categories of base-line alcohol consumption, adjusting for other risk factors, and related drinking and smoking habits to the cumulative probability of dying between the ages of 35 and 69 years.
Results Causes of death associated with drinking were cirrhosis and alcoholism ; cancers of the mouth, esophagus, pharynx, larynx, and liver combined ; breast cancer in women ; and injuries and other external causes in men.
The mortality from breast cancer was 30 percent higher among women reporting at least one drink daily than among nondrinkers (relative risk, 1.3 ; 95 percent confidence interval, 1.1 to 1.6).
The rates of death from all cardiovascular diseases were 30 to 40 percent lower among men (relative risk, 0.7 ; 95 percent confidence interval, 0.7 to 0.8) and women (relative risk, 0.6 ; 95 percent confidence interval, 0.6 to 0.7) reporting at least one drink daily than among nondrinkers, with little relation to the level of consumption.
The overall death rates were lowest among men and women reporting about one drink daily. (...)
Mots-clés Pascal : Alcoolisme, Epidémiologie, Mortalité, Etats Unis, Amérique du Nord, Amérique, Adulte, Homme, Vieillard, Etiologie, Facteur risque, Appareil circulatoire pathologie, Sexe, Analyse multivariable
Mots-clés Pascal anglais : Alcoholism, Epidemiology, Mortality, United States, North America, America, Adult, Human, Elderly, Etiology, Risk factor, Cardiovascular disease, Sex, Multivariate analysis
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0048231
Code Inist : 002B18C05B. Création : 14/05/1998.