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  1. Silicone breast implants and systemic rheumatic disease : Some smoke but little fire to date.

    Article - En anglais

    For over 20 years, silicone breast implants have been used for cosmetic and breast reconstruction purposes.

    They have been recently banned by the American Food and Drug Administration other than for reconstruction or in the setting of a study.

    Complications of rupture, leaking, bleeding, capsular thickening and contracture are acknowledged but the potential of silicone implants in causing classic rheumatic diseases or a new syndrome has caused much controversy ; there are millions of dollars at stake in legal suits.

    The biological plausibility of silicone breast implants causing disease is not without merit.

    The epidemiological evidence linking the two are reviewed.

    There is considerable concern as to whether there will ever be a definitive study of the question.

    Mots-clés Pascal : Chirurgie, Implant, Siloxane polymère, Glande mammaire, Femelle, Complication, Tissu conjonctif maladie mixte, Dermatomyosite, Sclérodermie, Polyarthrite rhumatoïde, Lupus érythémateux, Disséminé, Epidémiologie, Homme, Biomatériau, Chronique, Peau pathologie, Appareil circulatoire pathologie, Appareil respiratoire pathologie, Système ostéoarticulaire pathologie, Muscle strié pathologie, Maladie système, Tissu conjonctif pathologie, Rhumatisme inflammatoire, Immunopathologie, Maladie autoimmune

    Mots-clés Pascal anglais : Surgery, Implant, Siloxane polymer, Mammary gland, Female, Complication, Sharp syndrome, Dermatomyositis, Scleroderma, Rheumatoid arthritis, Lupus erythematosus, Disseminated, Epidemiology, Human, Biomaterial, Chronic, Skin disease, Cardiovascular disease, Respiratory disease, Diseases of the osteoarticular system, Striated muscle disease, Systemic disease, Connective tissue disease, Inflammatory joint disease, Immunopathology, Autoimmune disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0047774

    Code Inist : 002B07. Création : 14/05/1998.