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  1. Statistical evaluation of the role of Helicobacter pylori in stress gastritis : Applications of splines and bootstrapping to the logistic model.

    Article - En anglais

    Stress gastritis is a serious problem in the intensive care unit population.

    The recent discovery of the causal nature of Helicobacter pylori (H. pylori) in the development of gastric ulcers led us to examine its relationship with stress gastritis.

    We investigated this relationship in 874 veterans admitted to intensive care units who were tested for the presence of H. pylori and followed for 6 weeks for the development of stress gastritis.

    We fit spline models to assess functional relationships and used the logistic model to determine the association between H. pylori and stress gastritis.

    The predictive ability of the model was assessed with receiver operating characteristic (ROC) curve analysis and validated with the bootstrapping technique.

    Increased anti-H. pylori immunoglobulin A concentrations were found to be an important predictor of stress gastritis independent of other known risk factors.

    Mots-clés Pascal : Gastrite, Stress, Helicobacter pylori, Spirillaceae, Spirillales, Bactérie, Facteur risque, Analyse statistique, Vieillard, Homme, Régression logistique, Bootstrap, Spline, Prédiction, Modèle statistique, Méthode ROC, Appareil digestif pathologie, Estomac pathologie

    Mots-clés Pascal anglais : Gastritis, Stress, Helicobacter pylori, Spirillaceae, Spirillales, Bacteria, Risk factor, Statistical analysis, Elderly, Human, Logistic regression, Bootstrap, Spline, Prediction, Statistical model, Receiver operating characteristic curves, Digestive diseases, Gastric disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0044468

    Code Inist : 002B13B03. Création : 14/05/1998.