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  1. Relation of smoking and alcohol and coffee consumption to active Helicobacter pylori infection : cross sectional study.

    Article - En anglais

    Objective 

    To assess the relation of smoking and alcohol and coffee consumption to active Helicobacter pylori infection.

    Design 

    Cross sectional study of patients attending a general practitioner.

    Active H pylori infection was measured by the 13C-urea breath test and detailed quantitative information on smoking and on alcohol and coffee consumption was obtained by a standardised self administered questionnaire.

    Setting 

    One general practice in Germany.

    Subjects 

    447 patients aged 15-79 who had not had peptic ulcer disease or treatment for H pylori infection.

    Main outcome measures 

    Prevalence of H pylori infection according to smoking and alcohol and coffee consumption.

    Results 

    Overall prevalence of infection was 21% (94/447).

    There was no significant relation between smoking and active H pylori infection.

    Alcohol consumption showed a negative dose-response relation and coffee consumption a positive dose-response relation with active infection.

    After adjustment for potential confounders, the odds ratios for patients who drank ¾75 g and>75 g of ethanol a week compared with non-drinkers were 0.90 (95%) confidence interval 0.55 to 1.59) and 0.33 (0.16 to 0.68), respectively (P value for trend 0.005, assuming that 1 litre of beer and 0.5 1 of wine contain on average 50 g of ethanol in south Germany).

    Adjusted odds ratios for patients who drank<3 cups and =3 cups of coffee per day compared with those who did not drink coffee were 1.49 (0.71 to 3.12) and 2.49 (1. (...)

    Mots-clés Pascal : Helicobacter pylori, Spirillaceae, Spirillales, Bactérie, Infection, Tabagisme, Consommation alimentaire, Boisson alcoolisée, Ethanol, Café, Epidémiologie, Facteur risque, Homme, Allemagne, Europe

    Mots-clés Pascal anglais : Helicobacter pylori, Spirillaceae, Spirillales, Bacteria, Infection, Tobacco smoking, Food intake, Alcoholic beverage, Ethanol, Coffee, Epidemiology, Risk factor, Human, Germany, Europe

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0043429

    Code Inist : 002B05B02F. Création : 17/04/1998.