To assess the relation of smoking and alcohol and coffee consumption to active Helicobacter pylori infection.
Cross sectional study of patients attending a general practitioner.
Active H pylori infection was measured by the 13C-urea breath test and detailed quantitative information on smoking and on alcohol and coffee consumption was obtained by a standardised self administered questionnaire.
One general practice in Germany.
447 patients aged 15-79 who had not had peptic ulcer disease or treatment for H pylori infection.
Prevalence of H pylori infection according to smoking and alcohol and coffee consumption.
Overall prevalence of infection was 21% (94/447).
There was no significant relation between smoking and active H pylori infection.
Alcohol consumption showed a negative dose-response relation and coffee consumption a positive dose-response relation with active infection.
After adjustment for potential confounders, the odds ratios for patients who drank ¾75 g and>75 g of ethanol a week compared with non-drinkers were 0.90 (95%) confidence interval 0.55 to 1.59) and 0.33 (0.16 to 0.68), respectively (P value for trend 0.005, assuming that 1 litre of beer and 0.5 1 of wine contain on average 50 g of ethanol in south Germany).
Adjusted odds ratios for patients who drank<3 cups and =3 cups of coffee per day compared with those who did not drink coffee were 1.49 (0.71 to 3.12) and 2.49 (1. (...)
Mots-clés Pascal : Helicobacter pylori, Spirillaceae, Spirillales, Bactérie, Infection, Tabagisme, Consommation alimentaire, Boisson alcoolisée, Ethanol, Café, Epidémiologie, Facteur risque, Homme, Allemagne, Europe
Mots-clés Pascal anglais : Helicobacter pylori, Spirillaceae, Spirillales, Bacteria, Infection, Tobacco smoking, Food intake, Alcoholic beverage, Ethanol, Coffee, Epidemiology, Risk factor, Human, Germany, Europe
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0043429
Code Inist : 002B05B02F. Création : 17/04/1998.