Problem/Condition : The reported prevalence of anencephaly and spina bifida in the United States has steadily declined since the late 1960s.
During this time, the ability to diagnose these defects prenatally has progressed rapidly.
Many U.S. birth defects surveillance systems ascertain defects only among live-born infants or among infants and fetuses beyond a certain gestational age, thus excluding defects among pregnancies prenatally diagnosed as being affected by a neural tube defect (NTD) and electively terminated before the gestational age limit.
The impact of prenatal diagnosis and subsequent pregnancy termination on the reported prevalence of anencephaly and spina bifida in the United States has not been well established.
However, assessment of this impact is crucial to the use of surveillance data to monitor trends in the occurrence of NTDs and the effectiveness of interventions for these defects (e.g., increased consumption of folic acid).
Reporting Period :
This report presents data from birth defects surveillance systems in in six states over different time periods : Arkansas, 1985-1989 ;
California, 1989-1991 ;
Georgia, 1990-1991 ;
Hawaii, 1988-1994 ;
Iowa, 1985-1990 ;
and South Carolina, 1992-1993. (...)
Mots-clés Pascal : Tératologie, Surveillance sanitaire, Prénatal, Spina bifida, Homme, Diagnostic, Etats Unis, Amérique du Nord, Amérique, Epidémiologie, Prévalence, Anencéphalie, Gestation, Système ostéoarticulaire pathologie, Rachis pathologie, Maladie congénitale, Malformation
Mots-clés Pascal anglais : Teratology, Sanitary surveillance, Prenatal, Spina bifida, Human, Diagnosis, United States, North America, America, Epidemiology, Prevalence, Anencephaly, Pregnancy, Diseases of the osteoarticular system, Spine disease, Congenital disease, Malformation
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0040844
Code Inist : 002B17D. Création : 17/04/1998.