Excess mortality of schizophrenia : A meta-analysis.
Background This paper presents a structured review ofthe published information on the mortality of schizophrenia.
Method A meta-analysis ofthe literature.
Results Schizophrenia has a significantly increased mortality from natural and unnatural causes.
Twenty-eight per cent ofthe excess mortality is attributable to suicide and 12% to accidents.
The rest ofthe excess mortality is from the same broad range of conditions which cause deaths in the general population.
Further interpretation is hampered by confounding variables, wide confidence intervals and reservations about generalising from individual cohorts.
Conclusions The available evidence suggests that schizophrenia is associated with a large increased mortality from suicide and a moderate increased mortality from natural causes.
A number of possible interventions have been identified, but we do not yet have reliable means of detecting any changes in mortality which might result.
Mots-clés Pascal : Schizophrénie, Mortalité, Prévalence, Epidémiologie, Angleterre, Grande Bretagne, Royaume Uni, Europe, Pays de Galles, Métaanalyse, Article synthèse, Homme, Psychose
Mots-clés Pascal anglais : Schizophrenia, Mortality, Prevalence, Epidemiology, England, Great Britain, United Kingdom, Europe, Wales, Metaanalysis, Review, Human, Psychosis
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0039340
Code Inist : 002B18C06A. Création : 17/04/1998.