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  1. Retinal toxicity associated with occupational exposure to the fish anesthetic MS-222.

    Article - En anglais


    To report a case of retinopathy associated with chronic occupational exposure to ethyl-m-aminobenzoic acid methanesulfonate (MS-222), a retinotoxic fish anesthetic.


    Case report with electroretinograms to document changes in visual electrophysiology.


    An ichthyologist with a long history of skin exposure to MS-222 was initially examined for decreased vision, photophobia, and photopsia.

    His electroretinogram abnormalities were similar to those seen in animal models of acute MS-222 toxicity.

    After terminating MS-222 contact for 7 months, his vision returned to normal, and his electroretinogram improved.


    Individuals with occupational exposure to MS-222 should exercise caution to avoid systemic absorption of this retinotoxic compound.

    Mots-clés Pascal : Exposition professionnelle, Anesthésique, Pisces, Vertebrata, Toxicité, Oeil, Rétinopathie, Etude cas, Homme, Médecine travail, Oeil pathologie, MS-222

    Mots-clés Pascal anglais : Occupational exposure, Anesthetic, Pisces, Vertebrata, Toxicity, Eye, Retinopathy, Case study, Human, Occupational medicine, Eye disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0038457

    Code Inist : 002B30B01A. Création : 17/04/1998.