A study was undertaken to investigate the relationship between air pollution levels and respiratory symptoms and peak expiratory flow rate (PEFR) in subjects with chronic obstructive pulmonary disease (COPD) living in Christ-church, New Zealand.
Forty subjects aged over 55 years with COPD completed twice daily diaries for three months during the winter of 1994.
Subjects recorded respiratory symptoms, PEFR, outdoor activity, visits to doctor or hospital, and medication use.
All were resident within a 5 km radius of the regional council's air pollution monitoring site.
Daily and hourly mean pollutant levels (particulates (PM10), nitrogen dioxide (NO2), sulphur dioxide (SO2) and carbon monoxide (CO)) were measured at the monitoring site.
Pollution levels were generally low relative to those recorded in previous years.
The New Zealand Ministry for the Environment guidelines for PM10 were exceeded on five occasions, and for CO six times.
No association was found between PEFR and any of the pollution variables.
A rise in PM10 concentration equivalent to the interquartile range was associated with an increase in night time chest symptoms (relative risk 1.38,95% CI 1.07 to 1.78).
A rise in NO2 concentrations equivalent to the interquartile range was associated with increased reliever inhaler use (relative risk 1.42,95% CI 1.13 to 1.79) and for 24 hour lag analysis with increased nebuliser use (relative risk 2.81,95% CI 1.81 to 4.39). (...)
Mots-clés Pascal : Bronchopneumopathie obstructive, Chronique, Pollution air, Azote dioxyde, Carbone monoxyde, Nouvelle Zélande, Océanie, Débit expiratoire maximum, Toxicité, Homme, Appareil respiratoire pathologie, Poumon pathologie, Bronche pathologie
Mots-clés Pascal anglais : Obstructive pulmonary disease, Chronic, Air pollution, Nitrogen dioxide, Carbon monoxide, New Zealand, Oceania, Maximum expiratory flow rate, Toxicity, Human, Respiratory disease, Lung disease, Bronchus disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0037261
Code Inist : 002B11B. Création : 17/04/1998.