Biological monitoring of triethylamine among cold-box core makers in foundries.
The objectives of the study were to assess triethylamine (TEA) exposure in cold-box core making and to study the applicability of urinary TEA measurement in exposure evaluation.
Air samples were collected by pumping of air through activated-charcoal-filled glass tubes, and pre-and postshift urine samples were collected.
The TEA concentrations were determined by gas chromatography.
Tea was measured in air and urine samples from the same shift.
Breathing-zone measurements of 19 workers in 3 foundries were included in the study, and stationary and continuous air measurements were also made in the same foundries.
Pre-and postshift urine samples were analyzed for their TEA and triethylamine-N-oxide (TEAO) concentrations.
The TEA concentration range was 0.3-23 mg/m3 in the breathing zone of the core makers.
The mean 8-h time-weighted average exposure levels were 1.3,4.0, and 13 mg/m3 for the three foundries.
Most of the preshift urinary TEA concentrations were under the detection limit, whereas the postshift urinary TEA concentrations ranged between 5.6 and 171 mmol/mol creatinine.
The TEAO concentrations were 4-34% (mean 19%) of the summed TEA+TEAO concentrations.
The correlation between air and urine measurements was high (r=0.96, P<0.001).
A TEA air concentration of 4.1 mg/m3 (the current ACGIH 8-h time-weighted average threshold limit value) corresponded to a urinary concentration of 36 mmol/mol creatinine. (...)
Mots-clés Pascal : Procédé boite froide, Industrie métallurgique, Fonderie, Exposition professionnelle, Médecine travail, Homme, Surveillance biologique, Urine, Liquide biologique, Triéthylamine
Mots-clés Pascal anglais : Cold box process, Metallurgical industry, Foundry, Occupational exposure, Occupational medicine, Human, Biological monitoring, Urine, Biological fluid
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0028159
Code Inist : 002B03L06. Création : 17/04/1998.