A follow-up investigation was performed on 49 female workers studied 2 years earlier in a vegetable-pickling plant.
Acute and chronic respiratory symptoms and ventilatory capacity measurements were recorded during the original and the follow-up studies.
Maximal expiratory flow-volume (MEFV) curves were recorded during the Monday morning work shift.
The forced vital capacity (FVC), I-s forced expiratory volume (FEVI), and flow rates at 50% and the last 25% of the FVC (FEF50, FEF25) were measured.
There were small increases in the prevalence of chronic symptoms between the two studies for both smokers and nonsmokers, but these did not reach statistical significance.
Five workers at the time of the initial study had a diagnosis of occupational asthma ; only one of these was still working at the time of follow-up.
Workers lost to the follow-up had lower lung function than those seen at follow-up.
In workers who were followed, larger than expected mean annual declines were noted for all ventilatory capacity parameters in both smokers (FVC 0.070 1, FEV1 0.070 1 ; FEF50 0.3551/s, FEF25 0.2701/s) and nonsmokers (FVC 0.045 1, FEVI 0.0451, FEF50 0.285 1/s ; FEF25 0.1301/s).
The decrease was particularly pronounced for FEF50 and FEF25.
The accelerated decline in ventilatory capacity tests noted in the female nonsmokers suggests an independent effect on lung function of work exposure in this environment. (...)
Mots-clés Pascal : Acétique acide, Aérosol, Industrie alimentaire, Toxicité, Exposition professionnelle, Médecine travail, Homme, Débit expiratoire maximum 75,85, Débit expiratoire maximum 25,75, Fonction respiratoire, Réponse ventilatoire, Etude longitudinale, Inhalation, Appareil respiratoire pathologie
Mots-clés Pascal anglais : Acetic acid, Aerosols, Food industry, Toxicity, Occupational exposure, Occupational medicine, Human, Forced expiratory flow rate 75,85, Forced expiratory flow rate 25,75, Lung function, Ventilatory response, Follow up study, Inhalation, Respiratory disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0027302
Code Inist : 002B03L02. Création : 17/04/1998.