The purpose of this study was to estimate the proportion of pregnancies with pregestational diabetes in Germany, to compare the outcome of these pregnancies to pregnancies in nondiabetic mothers and to identify risk factors for poor pregnancy outcomes in mothers with pregestational diabetes.
Data of the « Perinatalerhebung Nordrhine » from 1988-1993 were analysed.
The Perinatalerhebung is an ongoing quality assurance programme of prenatal and perinatal care in the region of North Rhine (South Western part of North Rhine-Westphalia).
During the observation period a proportion of 93% - 100% of the annual births in the region (n=~100000) were included in the study.
Their data had been documented by the obstetricians in a standard multiple choice questionnaire.
The outcome parameters perinatal mortality, macrosomia, prematurity, and malformations were analysed in relation to several defined explanatory variables.
There were 2.402 births in mothers with pregestational diabetes (0.4% of all births).
The proportions of poor pregnancy outcomes in women with pregestational diabetes were 2.8% for perinatal mortality, 27.6% for macrosomia, 21.1% for prematurity and 2.1% for malformations.
The respective relative risks compared to the non diabetic mothers were 4.3 (95% CI 3.4-5.5) for perinatal mortality, 3.1 (95% CI 2.9-3.3) for macrosomia, 2.7 (95% CI 2.5 2.9) for prematurity and 1.7 (95% CI 1.3-2.3) for malformations. (...)
Mots-clés Pascal : Gestation, Etude comparative, Association, Diabète, Prévalence, Facteur risque, Prématurité, Etude longitudinale, Evaluation, Allemagne, Europe, Femelle, Homme, Appareil génital femelle pathologie, Endocrinopathie
Mots-clés Pascal anglais : Pregnancy, Comparative study, Association, Diabetes mellitus, Prevalence, Risk factor, Prematurity, Follow up study, Evaluation, Germany, Europe, Female, Human, Female genital diseases, Endocrinopathy
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0020564
Code Inist : 002B20F02. Création : 17/04/1998.