The impact of malnutrition in morbidity and mortality in stable haemodialysis patients.
When assessed by single biochemical measurements, malnutrition in dialysis patients is associated with increased mortality, but there are few data evaluating abnormalities in anthropometry or composite nutritional scores and outcome.
The aim of our study was to ascertain the prevalence and severity of malnutrition in 761 stable patients from 20 haemodialysis centres and its influence in morbidity and mortality after one year of follow-up.
Malnutrition was estimated by scoring four anthropometric indexes ; body mass index (BMI), triceps skinfold thickness (TSF), mid-arm circumference (MAC), and mid-arm muscle circumference (MAMC) ; three biochemical measurements ; serum albumin, serum transferrin and total lymphocyte count ; and clinical examination.
Mortality and hospitalizations were collected prospectively during the year of follow-up.
A moderate/severe degree of malnutrition was presented by 51.6% of male and 46.3% of female patients.
TSF was moderate-severely decreased in 41% without differences between males and females.
MAMC was moderately decreased in 19.8% of males and in 8.1% of females (P<0.001).
Multiple logistic regression analysis showed that the predictors of malnutrition were : age>65 years (OR=1.96, CI : 1.22-3,14), male sex (OR=1.95, CI : 1.24-3.07), comorbidity index (OR=1.23, CI : 1.03-1.45), time on dialysis (OR=1.13, CI : 1.08-1.18), duration of dialysis (OR=0.73, Cl : 0.63-0.85). (...)
Mots-clés Pascal : Hémodialyse, Prévalence, Facteur risque, Malnutrition, Mortalité, Morbidité, Protéine, Catabolisme, Analyse biochimique, Espagne, Europe, Homme, Evaluation, Epuration extrarénale, Trouble nutrition, Activité biologique
Mots-clés Pascal anglais : Hemodialysis, Prevalence, Risk factor, Malnutrition, Mortality, Morbidity, Protein, Catabolism, Biochemical analysis, Spain, Europe, Human, Evaluation, Extrarenal dialysis, Nutrition disorder, Biological activity
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0016495
Code Inist : 002B27B03. Création : 17/04/1998.