The aim of the study was to investigate the association of the use of commonly prescribed antibiotics with prevalence of Helicobacter pylori infection in a population of adult outpatients.
All patients aged 15-79 years who visited the practice of a general practitioner (GP) between June and September 1996 in a suburban community near Ulm, a city in southern Germany, were asked to participate in the study.
Infection status was determined with a 13C-urea breath test.
In addition, the patients were asked to fill out a self-administered questionnaire.
Overall, 475 outpatients were included in the study (response, 94.1%). A total of 266 patients (56.0%) reported a history of antibiotic treatment within the past 5 years, whereas 147 patients (30.9%) did not (62 patients (13.1%) did not know).
Prevalence of infection in patients with a history of antibiotic medication during the past 5 years was 23.3%, whereas the prevalence of infection was 20.4% in subjects without antibiotic treatment (P=0.283 after stratification for age).
Control for other potential confounders by multivariable analysis did not materially alter the results.
Coincidental antibiotic treatment is not associated with H. pylori prevalence in adults.
Mots-clés Pascal : Gastrite, Campylobactériose, Bactériose, Infection, Helicobacter pylori, Spirillaceae, Spirillales, Bactérie, Prévalence, Relation incertitude, Chimiothérapie, Antibactérien, Etude statistique, Homme, Appareil digestif pathologie, Estomac pathologie
Mots-clés Pascal anglais : Gastritis, Campylobacter infection, Bacteriosis, Infection, Helicobacter pylori, Spirillaceae, Spirillales, Bacteria, Prevalence, Uncertainty relation, Chemotherapy, Antibacterial agent, Statistical study, Human, Digestive diseases, Gastric disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0016112
Code Inist : 002B05B02F. Création : 17/04/1998.