Can we measure prior Postmenopausal estrogen/progestin use : The Postmenopausal Estrogen/Progestin Interventions Trial.
The objective of this study was to assess : 1) the accuracy of a single self-report question about postmenopausal estrogen use ; and 2) the performance and repeated measures agreement of a standardized hormone use interview.
Women (n=863) in the Postmenopausal Estrogen/Progestin Interventions Trial (PEPI) completed a self-report baseline questionnaire (BQ) at enrollment and a History of Hormone Use interview (HHU) at the 3-month follow-up visit (HHU3mos).
A subsample of 101 women completed a second HHU interview 3 years later (HHU3yrs).
As determined by the HHU3mos, 479 (56%) of women had ever used postmenopausal estrogen and 261 (30%) had ever used postmenopausal progestin.
The mean number of years since last estrogen or progestin use was 2.2 and 1.3 years, respectively.
Overall, there was 95% agreement between self-reported estrogen use on the BQ and the HHU3mos (kappa=0.91).
Using the HHU3mos as the criterion standard, the BQ misclassified 2.3% of women as false positives and 6.3% as false negatives.
The average duration of estrogen use in the false-negative classifications was 1.9 years (range : 1-9 years).
On the HHU3mos, 39.7% of participants could not recall at least one of the specific details of estrogen use (preparation, dose, route, or starting or stopping year) ; similar patterns of recall were found for progestin use.
Factors associated with discordant reporting of ever-use of ERT (BQ vs. (...)
Mots-clés Pascal : Oestrogène, Progestatif, Hormone stéroïde sexuelle, Chimiothérapie, Traitement substitutif, Autoévaluation, Rappel, Homme, Femelle, Ménopause, Méthodologie, Epidémiologie
Mots-clés Pascal anglais : Estrogen, Progestagen, Sex steroid hormone, Chemotherapy, Replacement therapy, Self evaluation, Recall, Human, Female, Menopause, Methodology, Epidemiology
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0007539
Code Inist : 002B30A01A1. Création : 17/04/1998.