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  1. Hepatocellular carcinoma and hepatic cirrhosis in Mexico : A 25 year necroscopy review.

    Article - En anglais


    Hepatocellular carcinoma (HCC) is a common form of cancer which is found throughout the world.

    In recent years, the rates of HCC seem to have increased in European and North American countries.

    Herein, a retrospective review of necroscopy records over a 25-year period was undertaken in order to determine the incidence of HCC in a Mexican population.


    A retrospective review of necroscopy records was performed to determine the incidence of HCC and then to determine the presence or absence of associated cirrhosis in these cases.

    The tumor/cirrhosis relationship was determined by computing the TC/T and TC/C indexes.


    Of 12556 autopsies studied, 73 cases of histologically proven HCC were reported, representing a total necropsy carcinoma incidence of 0.59%. Fifty-five cases were associated with cirrhosis (0.43%), and 18 were not (0.14%). HCC was two times more common in males (67%) than in females (33%), with a ratio of 2 : 1. During this period, the necropsy incidence ofHCC rose steadily to twice its original level (1965-69 incidence 0.35% ; 1985-89 incidence 0.69%). The necropsy incidence of cirrhosis was 4% (329 males, 185 females).

    The overall TC/T index was 75% (87% for males and 50% for females).

    The overall TC/C index was 10.7% (13% for males and 6.4% for females).


    There was a two-fold increase in the incidence of HCC in the Mexican population studied over a 25-year period. (...)

    Mots-clés Pascal : Carcinome hépatocellulaire, Incidence, Association morbide, Cirrhose, Foie, Evolution, Etude statistique, Homme, Appareil digestif pathologie, Foie pathologie, Tumeur maligne

    Mots-clés Pascal anglais : Hepatocellular carcinoma, Incidence, Concomitant disease, Cirrhosis, Liver, Evolution, Statistical study, Human, Digestive diseases, Hepatic disease, Malignant tumor

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0007462

    Code Inist : 002B13C01. Création : 17/04/1998.