Risk factors for gallbladder polyps in the Chinese population.
To assess the prevalence of and risk factors for gallbladder (GB) polyps in the Chinese population.
A prospective ultrasonographic study of GB polyps was conducted in 3647 Chinese subjects who received a paid physical checkup at this hospital.
Their demographic characteristics and biochemical parameters were recorded.
Ultrasonographic diagnosis revealed a normal GB in 2946 subjects (1838 men, 1108 women), polyps in 243 (174 men, 69 women), gallstones in 286 (196 men, 90 women), a history of cholecystectomy in 100 (56 men, 44 women), mixed gallstones/GB polyps in 17 (10 men, seven women), and miscellaneous results in 35.
Excluding subjects with cholecystectomy and mixed gallstones/GB polyps, the overall prevalence of GB polyps in the study group was 6.9%. The studied risk factors manifesting an increased odds ratio (OR) for the development of GB polyps were glucose intolerance (OR 1.506, p<0.05) and male gender (OR 1.723, p<0.05) in multivariate analysis.
Other demographic characteristics and biochemical parameters, such as age, body mass index, cigarette smoking, alcohol consumption, blood pressure, lipid profile, hepatitis B virus carrier, liver function, and parity, did not exhibit any correlation to GB polyps.
Among Chinese of higher socioeconomic status, men and individuals with glucose intolerance tend to have a high risk for developing GB polyps.
Mots-clés Pascal : Polype, Vésicule biliaire, Incidence, Echographie, Diagnostic, Facteur risque, Statut socioéconomique, Anomalie tolérance glucose, Etude statistique, Homme, Chine, Asie, Appareil digestif pathologie, Voie biliaire pathologie, Tumeur bénigne, Exploration ultrason
Mots-clés Pascal anglais : Polyp, Gallbladder, Incidence, Echography, Diagnosis, Risk factor, Socioeconomic status, Impaired glucose tolerance, Statistical study, Human, China, Asia, Digestive diseases, Biliary tract disease, Benign neoplasm, Sonography
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0007332
Code Inist : 002B13C03. Création : 17/04/1998.