To study cause specific mortality and cancer morbidity in workers exposed to the dust of grinding materials, grinding agents, and stainless steel, especially with regard to a possibly increased risk of respiratory, stomach, and colorectal cancer.
Methods-Retrospective cohort study, using reference cohorts of blue collar workers and population rates for comparison.
The exposed cohort comprises workers with at least 12 months employment time at two plants, producing stainless steel sinks and saucepans (n=727).
Also, reference cohorts of other industrial workers (n=3965) and fishermen (n=8092) were analysed.
The observation period began 15 years after the start of employment.
Standardised mortality or incidence ratios (SMRs, SIRs ; county reference rates) were calculated for cause-specific mortality between 1952 and 1993, and for cancer morbidity between 1958 and 1992.
In the exposed cohort, overall mortality, cardiovascular mortality, and all malignant mortality and morbidity were slightly lower than expected.
Also, the risk estimates for cancer in the upper and lower respiratory tracts and for stomach cancer were lower than expected.
There was an increase of morbidity from colon cancer, which was explained by an excess of tumours in the sigmoid part only.
Here, the risk estimates were higher in workers with long employment time (1-14 years : four observed cases, SIR 1.7,95% confidence interval (95% CI) 0.4 to 4. (...)
Mots-clés Pascal : Mortalité, Morbidité, Homme, Tumeur maligne, Côlon, Rectum, Prostate, Exposition professionnelle, Médecine travail, Poussière, Industrie métallurgique, Acier inoxydable, Broyage, Etude longitudinale, Appareil digestif pathologie, Intestin pathologie, Côlon pathologie, Rectum pathologie, Appareil génital mâle pathologie, Appareil urinaire pathologie, Prostate pathologie
Mots-clés Pascal anglais : Mortality, Morbidity, Human, Malignant tumor, Colon, Rectum, Prostate, Occupational exposure, Occupational medicine, Dust, Metallurgical industry, Stainless steel, Grinding(comminution), Follow up study, Digestive diseases, Intestinal disease, Colonic disease, Rectal disease, Male genital diseases, Urinary system disease, Prostate disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0007001
Code Inist : 002B13B01. Création : 17/04/1998.