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  1. Risk factors of Moyamoya disease in Canada and the USA.

    Article - En anglais

    Copyright (c) 1997 Elsevier Science B.V. All rights reserved.

    Over the past 28 years, 39 patients with Moyamoya disease or syndrome defined as spontaneous occlusion of the circle of Willis with extensive basal collateral vessels have been treated by the author in Canada and the USA.

    All patients presented with clinical or radiologic evidence of hemorrhage (23) or ischemia and infarction (16).

    A total of 12 patients had associated cerebral aneurysms and seven of these patients with aneurysms presented with subarachnoid hemorrhage.

    The patients ages ranged from 5 to 47 years.

    Of these 58% were female.

    The patients racial origin included North American Indian, Innuit, East Indian/Pakistani, Japanese, Chinese, Filipino, Korean, Malayasian, Hispanic, African American and Caucasian.

    Familial clustering was seen in North American Indian, Innuit and Caucasian patients.

    Associated disorders (tuberculosis, pharyngitis, thalassemia, fibromuscular hyperplasia, polycystic kidney, sickle cell trait and hypertension) were common in these patients, as was the use of tobacco, alcohol and in the adult females, oral contraceptives.

    It may be concluded from this series that the etiology of Moyamoya disease or syndrome is probably multifactorial, but that some racial and familial groups are more susceptible. (...)

    Mots-clés Pascal : Nishimoto Kudo maladie, Etats Unis, Amérique du Nord, Amérique, Canada, Age, Ethnie, Association morbide, Epidémiologie, Facteur risque, Homme, Encéphale pathologie, Système nerveux central pathologie, Système nerveux pathologie, Appareil circulatoire pathologie, Vaisseau sanguin pathologie, Cérébrovasculaire pathologie

    Mots-clés Pascal anglais : Nishimoto Kudo disease, United States, North America, America, Canada, Age, Ethnic group, Concomitant disease, Epidemiology, Risk factor, Human, Cerebral disorder, Central nervous system disease, Nervous system diseases, Cardiovascular disease, Vascular disease, Cerebrovascular disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0006957

    Code Inist : 002B17C. Création : 17/04/1998.