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  1. Predictors of interest in prostate-specific antigen screening and the impact of informed consent : What should we tell our patients ?

    Article - En anglais


    Screening for prostate cancer with the prostate-specific antigen (PSA) remains highly controversial.

    We sought to discern which patient factors predict interest in the PSA and how informed consent impacts these predictors.


    In a randomized trial that found that informed consent decreases patient interest in PSA screening, potential predictors of interest were analyzed separately in the uninformed (n=102) and informed (n=103) cohorts to examine the effects of the informational intervention.


    Univariate predictors of PSA screening interest (P<0.05) among uninformed patients included perceived efficacy of screening, perceived seriousness of an abnormal PSA, and willingness to accept treatment risks.

    Among patients who had been informed about PSA screening, univariate predictors included family history of prostate cancer, perceived susceptibility to prostate cancer, age (inverse association), and perceived efficacy, although informed patients rated PSA efficacy significantly lower than uninformed patients (P<0.001).

    In multivariate logistic regression modeling for the uninformed cohort, perceived screening efficacy (P<0.001), perceived seriousness (P<0.05), and willingness to accept treatment risks (P<0.05) together were significant predictors of PSA screening interest.

    Among informed patients, perceived efficacy (P<0.001), perceived susceptibility (P=0.01), and younger age (P=0.01) together predicted interest in screening. (...)

    Mots-clés Pascal : Tumeur maligne, Prostate, Antigène spécifique prostate, Dépistage, Diagnostic, Consentement éclairé, Etude comparative, Intérêt, Homme, Mâle, Prévention, Appareil génital mâle pathologie, Appareil urinaire pathologie, Prostate pathologie

    Mots-clés Pascal anglais : Malignant tumor, Prostate, Prostate specific antigen, Medical screening, Diagnosis, Informed consent, Comparative study, Interest, Human, Male, Prevention, Male genital diseases, Urinary system disease, Prostate disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0006794

    Code Inist : 002B20B02. Création : 17/04/1998.