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  1. Decreasing hepatitis D virus infection in Taiwan : An analysis of contributory factors.

    Article - En anglais

    Superinfection of hepatitis D virus (HDV) among hepatitis B virus (HBV) carriers is mainly through heterosexual contact in Taiwan.

    This study investigated the change of HDV endemicity and its associated contributory factors.

    Seventy-seven patients with acute HDV superinfection among 527 consecutive exacerbating hepatitis B surface antigen (HBsAg) carriers were identified over the past 12 years.

    The prevalence decreased significantly by each 3-year period from June 1983 to May 1995 (23.7,15.5,13.1 and 4.2%, respectively, P<0.001).

    This trend was more significant in the hepatitis B e antigen (HBeAg) - negative group (P<0.001) than in the HBeAg-positive group (P=0.073).

    Subjects with a history of paid sex and prostitutes were also recruited for analysis both in 1989 and 1996.

    Although not statistically significant, there was a trend showing a decrease in the prevalence of serum antibody against HDV (anti-HDV) in each risk group : it was lower in 1996 among HBsAg-positive brothel-goers (10.3 vs 6.9%), licensed prostitutes (54.5 vs 50%) and unlicensed prostitutes (36.1 vs 30.8%). Accumulation of anti-HDV-positive subjects in risk groups may mask the actual decrease of new HDV-infected cases.

    The prevalence of the HBsAg carrier rate among all prostitutes has significantly decreased (18.3 vs 12.2%, P=0.015).

    The efficacy of each preventive strategy was examined and mapped with the trend. (...)

    Mots-clés Pascal : Hépatite virale delta, Virose, Infection, Virus hépatite ni A ni B, Virus, Incidence, Evolution, Facteur correction, Prévention, Maladie sexuellement transmissible, Epidémiologie, Homme, Appareil digestif pathologie, Foie pathologie

    Mots-clés Pascal anglais : Viral hepatitis delta, Viral disease, Infection, Non A non B hepatitis virus, Virus, Incidence, Evolution, Correction factor, Prevention, Sexually transmitted disease, Epidemiology, Human, Digestive diseases, Hepatic disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0006262

    Code Inist : 002B30A01A2. Création : 17/04/1998.