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  1. Low blood pressure associated with low mood : A red herring ?

    Article - En anglais

    Objective

    Several reports have discussed a relationship between blood pressure (BP) and psychological well-being scales.

    Lower BP readings were associated with higher levels of psychological distress and fatigue.

    This study sought to replicate the association found by previous secondary analyses of epidemiological surveys.

    Design

    Cross-sectional study.

    Setting.

    Academic Family Medicine Department in Toronto, Canada.

    Subjects

    214 practice attenders.

    Study measures

    Extent of psychological abnormalities with the General Health Questionnaire (GHQ), self-reported fatigue, in-clinic and home BP measurements.

    Results

    No significant relationship between blood pressure levels and GHQ-score or fatigue could be demonstrated.

    This applies to clinic and home measurements for systolic and diastolic pressure.

    Neither adjustment for age or sex nor for several confounders through multiple linear regression produced significant associations in the postulated direction.

    No nonlinear relationship could be shown either.

    The study had a power of 95% to detect a correlation of r=0.22 (alpha=0.05, one-sided).

    Conclusion

    The study, specifically addressing the possible link between blood pressure and psychological dysfuntion/fatigue, could not confirm the previously reported association.

    Prohlems related to type-l error in epidemiological research are discussed.

    Mots-clés Pascal : Pression sanguine, Hémodynamique, Epidémiologie, Bien être psychologique, Fatigue, Trouble humeur, Homme, Détresse psychologique

    Mots-clés Pascal anglais : Blood pressure, Hemodynamics, Epidemiology, Psychological well being, Fatigue, Mood disorder, Human

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0003889

    Code Inist : 002B18C07D. Création : 17/04/1998.