The impact of body weight on all-cause mortality is subject to ongoing debate.
We assessed the relation between body mass index (BMI) and all-cause mortality in a cohort of 8043 male employees in the German construction industry who underwent detailed occupational health examinations at ages 25-64 and who were followed for all cause mortality over an average period of 4.5 years.
Overall, there was a negative, graded relation between BMI and all-cause mortality, which persisted after controlling for multiple covariates including age and cigarette smoking, and after excluding the initial two years of follow-up.
There was a strong positive cross-sectional relationship between BMI and a medical diagnosis of diabetes, hypertension, and ischemic heart disease at the baseline examination.
While BMI showed a strong negative relation with all-cause mortality among men with such diseases, the association was much weaker and non-monotonic for men free of these diseases.
Our results underline the importance of preexisting diseases for the prognostic value of body weight.
Mots-clés Pascal : Mortalité, Obésité, Poids corporel, Indice masse corporelle, Etude cohorte, Homme, Mâle, Industrie construction, Allemagne, Europe, Epidémiologie, Etat nutritionnel, Trouble nutrition
Mots-clés Pascal anglais : Mortality, Obesity, Body weight, Body mass index, Cohort study, Human, Male, Construction industry, Germany, Europe, Epidemiology, Nutritional status, Nutrition disorder
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0003233
Code Inist : 002B30A01A2. Création : 17/04/1998.