In a cohort of some 11 000 men born 1891-1920 and employed in the Quebec chrysotile production industry, including a small asbestos products factory, of 9780 men who survived into 1936,8009 are known to have died before 1993,38 probably from mesothelioma-33 in miners and millers and five in factory workers.
Among the 5041 miners and millers at Thetford Mines, there had been 4125 deaths from all causes, including 25 (0.61%) from mesothelioma, a rate of 33.7 per 100 000 subject-years ; the corresponding figures for the 4031 men at Asbestos were eight out of 3331 (0.24%, or 13.2 per 100 000 subject-years).
At the factory in Asbestos, where all 708 employees were potentially exposed to crocidolite and/or amosite, there were 353 deaths, of which five (0.90%) were due to mesothelioma ; the rate of 46.2 per 100 000 subject-years was 3.5 times higher than among the local miners and millers.
Six of the 33 cases in miners and millers were in men employed from 2 to 5 years and who might have been exposed to asbestos elsewhere ; otherwise, the 22 cases at Thetford were in men employed 20 years or more and the five at Asbestos for at least 30 years.
The cases at Thetford were more common in miners than in millers, whereas those at Asbestos were all in millers. (...)
Mots-clés Pascal : Carcinogène, Amiante, Fibre minérale, Chrysotile, Mine, Mésothéliome malin, Toxicité, Homme, Exposition professionnelle, Médecine travail, Industrie extractive, Québec, Canada, Amérique du Nord, Amérique, Epidémiologie, Etude cohorte, Tumeur maligne, Amphibole, Trémolite
Mots-clés Pascal anglais : Carcinogen, Asbestos, Mineral fiber, Mine, Malignant mesothelioma, Toxicity, Human, Occupational exposure, Occupational medicine, Mining industry, Quebec, Canada, North America, America, Epidemiology, Cohort study, Malignant tumor, Amphibole
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0002076
Code Inist : 002B11A. Création : 17/04/1998.