Glutaraldehyde is commonly used in hospitals for cold disinfection of instruments which may be damaged by autoclaving.
The increased use of automatic washer/disinfection machines has resulted in a greater risk of spills than with manual methods.
A series of experiments was conducted to answer two related research questions : what was the likely range of airborne concentrations when glutaraldehyde is spilled, and are commonly used personal protective equipment ensembles effective and practicable in use ?
Objective measurements using three sampling methods (two pumped methods based on OSHA 64, one using treated filters and the other based on adsorbent tubes, and a Glutaraldemeter direct reading instrument) were conducted with spills of various surface areas of both 2 and 50% solutions of glutaraldehyde.
Results ranged between<0.01 and 1.4 ppm.
Two personal protective equipment ensembles were tested.
One was based on a half-facepiece respirator with gas-tight goggles, while the other comprised a full-facepiece cartridge respirator.
Both ensembles gave adequate protection against irritation, although in use the half-facepiece respirator and goggles tended to interfere with each other.
The direct reading instrument generally underestimated the glutaraldehyde concentrations, although there was a significant association with the results obtained using the method based on adsorbent tubes.
Mots-clés Pascal : Glutaral, Antimicrobien, Désinfectant, Exposition professionnelle, Médecine travail, Hôpital, Personnel sanitaire, Accident travail, Déversement, Vêtement protection, Teneur air ambiant, Prévalence, Incidence, Evaluation, Homme
Mots-clés Pascal anglais : Glutaral, Antimicrobial agent, Disinfecting agent, Occupational exposure, Occupational medicine, Hospital, Health staff, Occupational accident, Spill, Safety clothing, Ambient air concentration, Prevalence, Incidence, Evaluation, Human
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0002074
Code Inist : 002B02U10. Création : 17/04/1998.